Blue rubber Bleb Nevus syndrome, or Bean's syndrome is a very rare disease characterized by an association of ①hemangioma cutis in which the nevi feel like rubber blebs; ② hemangiomas of the digestive organs; ③iron-deficiency anemia due to
hemorrhage
from the digestive tract. Sometimes, the bleeding is so severe and massive that the patient needs blood transfusion and/or emergency operations.
We present a 29-year-old man with Blue Rubber Bleb Nevus syndrome. This patients was admitted to our hospital due to recently aggrevated dizziness and intermittent rectal bleeding. Multiple bluish tumors were noted on the palm, sole and glans
penis.
Laboratory examination revealed severe iron-deficiency anemia. Barium studies revealed multiple polypoid masses in the stomach, small bowel and colorectum. On esophagogastroduodenscopy and colonoscopy, three or four dozens of hemangiomas with
variable
size and shape were noted in the stomach, duodenum at or around the ampulla of Vater and colorectum. This patient was of particular interest because rectal bleeding occurred from rectal lesion which protruded out of anus and caused bleeding
during
defection, and with showed as a 2.0 cm Yamada type III polypoid lesion. Endoscopic ultrasonography confirmed us that this lesion was confined to the mucosa and submucosa without extension into muscle layer. Endoscopic polypectomy of this lesion
was
performed because which considered as the main focus of current rectal bleeding . He was discharged without any complication and 4 months later, he was well without rectal bleeding and his hemoglobin level increased upto 13.5 g/dl. To our
knowledge,
this is the first case of Blue Rubber Bleb Nevus syndrome in Korea.
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